Development of a molecular diagnosis technique (comprising array CGH) on fetal cells from endocervical samples.
Julie Désir, MD PhD
Associate Professor, Head of the Prenatal and Reproductive Genetics Clinic
Bruno Pichon, PhD
Genetics Laboratory Supervisor
Labo of hospitaal waar het project plaatsvindt
Erasme Hospital, Laboratoy of Cytogenetic
Human Genetics Center – ULB
808 route de Lennik,
Objectives of research
Aim of this project is to offer, to couples with a child affected by genetic disease and/or carriers of a genetic abnormality, an innovative prenatal diagnosis method which has as main advantages:
- To be not invasive, from cervical smear which is an easy non-invasive test.
- To be realized early in pregnancy from 5 weeks of gestation
- To provide fetal genetic material from trophoblast cells in endocervical samples, which would allow to realize molecular genetic analyses and to detect small fetal genetic abnormalities.